Neurological abnormalities and cognitive ability in first-episode psychosis

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Neurological abnormalities and cognitive ability in first-episode psychosis.

BACKGROUND It remains unclear if the excess of neurological soft signs, or of certain types of neurological soft signs, is common to all psychoses, and whether this excess is simply an epiphenomenon of the lower general cognitive ability present in psychosis. AIMS To investigate whether an excess of neurological soft signs is independent of diagnosis (schizophrenia v. affective psychosis) and...

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OBJECTIVE There is widespread consensus that the EEG is not useful for the detection of clinically relevant abnormalities in patients with psychosis. Given that the EEG records brain dysfunction, this study examines whether an abnormal EEG in first-episode psychosis patients is associated with poorer prognosis, compared with a normal EEG. METHOD At their initial assessment, 61 patients with f...

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BACKGROUND Grey matter and other structural brain abnormalities are consistently reported in first-onset schizophrenia, but less is known about the extent of neuroanatomical changes in first-onset affective psychosis. AIMS To determine which brain abnormalities are specific to (a) schizophrenia and (b) affective psychosis. METHOD We obtained dual-echo (proton density/T2-weighted) magnetic r...

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Neurological soft signs in adolescents with first episode psychosis.

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ژورنال

عنوان ژورنال: British Journal of Psychiatry

سال: 2008

ISSN: 0007-1250,1472-1465

DOI: 10.1192/bjp.bp.107.045450